Azo compounds
Ambeed N1 N1 N2 N2Tetramethyldiazene1
N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide, 10465-78-8, 97%
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 100 MG
CAY 10465 is a selective and high-affinity Aryl Hydrocarbon Receptor (AhR) agonist, with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). In vitro, CAY 10465 (at concentrations from 0.01 nM to 100 μM) has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit the synthesis of this protein.
- Selective AhR agonist: High affinity for AhR with a Ki of 0.2 nM.
- No estrogen receptor effect: Shows no activity on the estrogen receptor (Ki >100000 nM).
- Inhibits apolipoprotein A-I: Reduces apo A-I levels and inhibits its synthesis in HepG2 cells.
- Appearance: Solid, white to off-white.
- Storage:
Powder: -20°C for 3 years, 4°C for 2 years.
In solvent: -80°C for 2 years, -20°C for 1 year.
Cambridge Isotope Laboratories 2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
Ambeed N1 N1 N2 N2Tetramethyldiazene1
N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide, 10465-78-8, 97%
![Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244741.png-250.jpg)
Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML
KW-2449 is a multi-targeted small-molecule kinase inhibitor active against FLT3, ABL (including ABL T315I), and Aurora kinases. It exhibits low-nanomolar potency and is supplied for laboratory research use.
- Multi-targeted kinase inhibitor effective against FLT3, ABL, and Aurora kinases.
- Low-nanomolar potency with reported IC50s of 6.6, 14, 4, and 48 nM (FLT3, ABL, ABL T315I, Aurora).
- Provided as a 10 mM solution in DMSO (1 mL) or as a solid in multiple milligram sizes.
- High purity suitable for research (reported purity 99.9%).
- Molecular formula C20H20N4O; molecular weight 332.40 g·mol⁻¹.
- For research use only; not for human or veterinary use.
![Medchemexpress LLC [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol-1 | C20H20N4O | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244548.png-250.jpg)
Medchemexpress LLC [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol-1 | C20H20N4O | 100 MG
KW-2449 is a small-molecule, multi-targeted kinase inhibitor used in research to study signaling pathways and leukemia models. Supplied as a high-purity white powder, it is characterized by the molecular formula C20H20N4O and a molecular weight of 332.40 g·mol-1.
- Multi-targeted kinase inhibition: inhibits FLT3, ABL, ABL T315I, and Aurora kinases at low nanomolar IC50s.
- High purity: reported 99.91% purity suitable for biochemical and cell-based assays.
- Solid powder form: convenient for dissolution in common organic solvents and buffers.
- Well-characterized: SMILES and molecular properties available for computational and analytical use.
- For research use only: not intended for human or clinical use.